Cancer BiologybioRxivPreprint
MELK controls tumor metabolism to promote resistance to melanoma therapy
Ana Carolina Bastos Sant'Anna Silva, Patricia Abbe, Sophie Pagnotta…·Stéphane Rocchi
This study identifies MELK as a key driver of metabolic adaptation and therapy resistance in melanoma, showing that inhibiting MELK can sensitize resistant cells to immunotherapy.
DOI 10.64898/2025.12.31.697178