Aaron H. Phillips

The paper develops a machine learning model to predict IDR condensation behavior, finding ~12% of human IDRs likely form condensates, enriched in RNA-related and membrane-less organelle functions.

This study identifies mTORC3, a rapamycin-resistant mTOR complex that requires ETV7 binding, and shows that specific mTOR and ETV7 domains mediate this interaction, with implications for cancer therapy.