Benjamin Lang

The paper develops a machine learning model to predict IDR condensation behavior, finding ~12% of human IDRs likely form condensates, enriched in RNA-related and membrane-less organelle functions.

AlphaSync provides updated AlphaFold structure models for 39,961 UniProt proteins and enhances 2.6 million structures with residue-level features.

The paper investigates how protein conformational dynamics reveal hidden post-translational modification sites and their functional relevance across timescales.

DEWSeq improves eCLIP data analysis by increasing the detection of RNA-binding protein binding sites and their functional elements.

This paper presents a high-sensitivity targeted method to measure pri-miRNA processing efficiency in clinical samples and identifies 24 microRNAs with significant changes in processing efficiency between normal liver and hepatocellular carcinoma.

The paper identifies scaffolding RNAs and a new player, TRA2A, in Fragile X-associated Tremor/Ataxia Syndrome by studying RNA-RBP interactions and their aggregation.