Author

Ava Bryan

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:Hi-C· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Pippa F. CosperiD· 2 shared Beth A. A. WeaveriD· 1 shared Diego Eyzaguirre· 1 shared Elizabeth Boulanger· 1 shared Emily McCunn· 1 shared Floris P BartheliD· 1 shared Jun Wan· 1 shared Kathryn M. JonesiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Pippa F. CosperORCID

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2 papers

Recent·Most cited

Telomere Dysfunction in Human Astrocytes Drives Acrocentric Chromosome Instability and Nucleolar Reorganization

Ogechukwu Mbegbu, Yi-An Chen, Yue Hao, Noelle H. Fukushima, T. Rhyker Ranallo-Benavidez, Ava Bryan, Szehoi Chan, Nikki N. Messick, Maria Kyriakidou, Tianpeng Zhang, Pippa F. Cosper, Floris P Barthel

This study shows that telomere dysfunction in human astrocytes leads to acrocentric chromosome instability and nucleolar reorganization through a combination of cytogenetic, imaging, and chromatin-contact analyses.

bioRxiv · May 21, 2026 · PreprintCancer Biology

Chromosomal instability increases radiation sensitivity

Pippa F. Cosper, Maha Paracha, Kathryn M. Jones, Laura Hrycyniak, Les Henderson, Ava Bryan, Diego Eyzaguirre, Emily McCunn, Elizabeth Boulanger, Jun Wan, Kwangok P. Nickel, Vanessa L. Horner, Rong Hu, Paul M. Harari, Randall J. Kimple, Beth A. A. Weaver

The paper shows that higher chromosomal instability (CIN) in cancer cells and tumors increases sensitivity to radiation, both directly and through drug-induced CIN mechanisms.

International Journal of Radiation Oncology*Biology*Physics · Jan 21, 2026Peer-reviewedCancer Biology