Miho Ohsugi

This study shows that RAD51 accumulates on non-damaged chromosomes in aging oocytes, leading to chromosome segregation failure and meiosis I arrest.

The paper shows that a balanced DNA-to-cytoplasm ratio, rather than genome ploidy, is critical for mouse embryos to reach the morula stage.

This study reconstitutes a nucleus in giant unilamellar vesicles using Xenopus egg extract, demonstrating functional nuclear import and pore complexes.

The paper shows that Ca2+ oscillations drive cytoplasmic backflow, which helps maintain spindle position during fertilized mouse egg division.