Jennifer Keiser

This study shows that ivermectin and moxidectin exposure leads to genomic and transcriptomic changes in bacteria, including ribosome modulation and resistance gene adjustments.

This study identifies consistent taxonomic and functional gut microbiota changes associated with Trichuris trichiura infection across three countries, revealing shared ecological responses and metabolic impacts.

The paper uses hybrid sequencing to analyze the off-target effects of antiparasitic drugs on the human gut microbiome, finding that ivermectin-albendazole significantly alters microbial composition and function.

This study shows that ivermectin and moxidectin inhibit gut bacterial growth and induce antibiotic-like resistance, raising concerns about cross-resistance to other antibiotics.

This paper introduces a nanopore sequencing workflow for high-quality, full-length 16S rDNA amplicons to identify bacterial isolates and profile microbial communities, showing high agreement with MALDI-TOF and strong correlation with Illumina sequencing.

The paper uses nanopore sequencing to identify two genetically distinct Trichuris species in humans and non-human primates, revealing geographic patterns and highlighting a new diagnostic marker for resource-limited settings.

This study identifies and characterizes a new human-infecting Trichuris species, Trichuris incognita n. sp., which shows resistance to albendazole-ivermectin treatment and suggests species-level differences in drug response rather than resistance.

This study evaluates SNPs in β-tubulin genes of human soil-transmitted helminths to assess their association with benzimidazole resistance, finding no strong evidence for their role as resistance markers.