James F.A. Poulet

This study identifies molecular changes in the naked mole-rat that enhance cold sensing through expanded TRPM8 expression and alternative cold detection mechanisms.

The paper identifies bidirectional thermoreceptors in mice that respond to both cool and warm temperatures, revealing their role in encoding innocuous thermal sensations.

The paper shows that simultaneous thermal and tactile stimuli enhance perception in mouse forepaw primary somatosensory cortex through changes in neuronal response dynamics and recruitment of silent neurons.

This study identifies distinct temperature representations in the somatosensory thalamus of mice, showing differences in cellular encoding and cortical output targets.

This study identifies sensory Schwann cells as critical for mechanosensation, showing they regulate touch and mechanical nociception.

This paper introduces a method to reuse patch-clamp pipettes by sonifying their tips in the bath solution, enabling at least 10 consecutive recordings without contaminating solutions or damaging brain slices.

The paper uses an optogenetic approach to measure dynamic and cell-type-specific chloride equilibrium potentials in rodent neurons.

This study identifies cortical neurons in mice that respond to cooling and warming, showing cool representation in primary somatosensory cortex and both cool and warm in posterior insular cortex.

The paper maps brain-wide connectivity of mouse thermosensory cortices, showing parallel input pathways and overlapping output regions for S1 and pIC.

The paper identifies two subcortical nuclei in mammals that organize fluid ingestion movements, showing their role in jaw and tongue control through stimulation and activity recordings.

This study shows that USH2A is essential for vibration sensing in mice and humans by being expressed in Meissner corpuscle end-organs, not in sensory neurons.

The paper shows mice can discriminate warm temperatures without dedicated thermoreceptors, using polymodal C-fibers and central circuits that integrate inputs from multiple afferents.

The paper describes a method for in vivo two-photon targeted whole-cell patch-clamp recordings of monosynaptically connected neurons in mice to study synaptic transmission and integration.