Author

Thomas H. Jonkman

Leiden University Medical CenterORCID 0000-0003-0307-6011Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Bastiaan T. HeijmansiD· 2 shared Erik W. van ZwetiD· 2 shared Lucia DaxingeriD· 1 shared Lucy SinkeiD· 1 shared Roderick C. SliekeriD· 1 shared Yunfeng LiuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Bastiaan T. HeijmansORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 12, 2025

Probing epigenetic clocks as a rational markers of biological age using blood cell counts

Thomas H. Jonkman, Erik W. van Zwet, Bastiaan T. Heijmans

The paper investigates how blood cell counts influence epigenetic age metrics, finding strong links with DNAmAge but weaker associations with AgeAccel, particularly for neutrophils in second-generation clocks.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsClinical EpigeneticsPeer-reviewedAug 25, 2023

The inactive X chromosome accumulates widespread epigenetic variability with age

Yunfeng Liu, Lucy Sinke, Thomas H. Jonkman…·Bastiaan T. Heijmans

The paper identifies age-related increases in DNA methylation variability on the inactive X chromosome in females and males, with aVMCs accumulating in XCI regions and showing replication in purified cell types.

22 citations

humanDNA methylation

𝕏 PostBluesky