Patricio Orio

This study shows serotonergic psychedelics like LSD and DMT delay resting state neurovascular coupling, affecting hemodynamic delays and functional connectivity in brain regions with serotonin receptors.

This study uses whole-brain modeling to show that structural brain hubs influence dynamical state transitions in disorders of consciousness.

This paper introduces a modified neural mass model with inhibitory synaptic plasticity to better simulate EEG and fMRI recordings during NREM sleep and capture the spectral richness of brain activity.

This study identifies a KCNC1 variant linked to Rett syndrome that disrupts ER to Golgi trafficking of Kv3.1 channels, affecting neuronal excitability.

This study investigates how noradrenaline and acetylcholine influence functional connectivity during NREM sleep stages using a whole brain model and empirical data.

The paper shows that odorant identity is encoded through nonlinear interactions in the olfactory system of rainbow trout, as revealed by information-theoretic metrics in LFPs.

This study shows that a natural ensemble of bacteria and amoebae induces diapause in C. elegans through RNA communication and pheromone signaling, with effects persisting across generations.

This study shows that brain networks with intermediate small-worldness exhibit the most dynamic behavior, with modularity strongly predicting neural dynamics.

This study uses a whole-brain model to show that video game expertise is linked to meso-scale functional connectivity changes and improved noise filtering in brain networks.

This study uses empirical fMRI and computational modeling to show that nicotine increases functional segregation in the brain during attentional tasks but not at rest, linking network topology to behavior.

This paper builds a whole-brain computational model to show that age-related changes in high-order functional interactions are explained by variations in the connectome.

The paper develops methods to analyze temporal relationships between peptidergic and motoneuronal activity during Drosophila ecdysis, revealing cross-frequency coupling and identifying a new post-ecdysis phase.

This paper uses a thalamocortical computational model to identify optimal auditory stimulation parameters for enhancing slow-wave sleep events like slow oscillations and spindles.

This study uses O-Information to analyze how high-order statistical interdependencies in fMRI data change with age, finding increased redundancy in older adults across brain regions.

The paper studies how cholinergic modulation of inhibitory interneurons affects functional integration in a whole-brain model using a human connectome.

The paper shows that the human connectome's core-shell structure enables graded ignition dynamics in cortical activity, which is not replicated by randomized connectomes.