Author

Evgenia N. Nikolova

Johns Hopkins UniversityORCID 0000-0003-0365-2939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Assay:DNA methylation· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Rutika PateliD· 2 shared Sharon M. LoverdeiD· 2 shared Abhik Ghosh MoulickiD· 1 shared Fabiana C. Malaga Gadea· 1 shared Helen K. Moos· 1 shared Sophie K Flaherty· 1 shared Tania Rajpersaud· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

Rutika PatelORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 21, 2026

DNA Sequence and Histone Variant H2A.Z Jointly Govern Nucleosome Unwrapping Pathways

Abhik Ghosh Moulick, Rutika Patel, Tania Rajpersaud…·Sharon M. Loverde

The paper shows DNA sequence and H2A.Z histone variant jointly determine nucleosome unwrapping directionality through simulations and NMR data.

DOI 10.64898/2026.06.15.732425

DNA methylationHi-C

𝕏 PostBluesky

BiophysicsbioRxivPreprintMay 13, 2026

Kaiso reads methylated CpGs at nucleosome entry/exit and displaces the H3 tail

Fabiana C. Malaga Gadea, Evgenia N. Nikolova

This study shows Kaiso binds methylated nucleosomes with position-specific affinity and displaces the H3 tail, suggesting a general mechanism for chromatin remodeling by DNA-binding factors.

DOI 10.64898/2026.05.10.724166

DNA methylationexperimental assay

𝕏 PostBluesky

BiophysicsNucleic Acids ResearchPeer-reviewedApr 11, 2026

H2A.Z facilitates Sox2-nucleosome interaction by promoting DNA and histone H3 tail mobility

Helen K. Moos, Rutika Patel, Sophie K Flaherty…·Evgenia N. Nikolova

This study investigates how H2A.Z affects Sox2 and Oct4 binding to nucleosomes by altering DNA and histone H3 tail dynamics.

2 citations

ChIP-seqmechanistic / dynamical model

𝕏 PostBluesky