Abhik Ghosh Moulick

The paper shows DNA sequence and H2A.Z histone variant jointly determine nucleosome unwrapping directionality through simulations and NMR data.

The paper develops a coarse-grained protein model that retains backbone dihedral angles, reproducing structural details from crystal structures and all-atom simulations.

This study uses molecular dynamics simulations to analyze how CENP-N interacts with CENP-A nucleosomes, revealing structural changes and their impact on conformational states and protein interactions.

This study compares all-atom and coarse-grained simulations of nucleosome dynamics using the SIRAH force field, revealing similar structural parameters but distinct conformational sampling and breathing motion in coarse-grained models.