ImmunologybioRxivPreprint
PDL-1+ Neutrophils mediate susceptibility during endotoxemia in Metabolic Dysfunction Associated Steatotic Liver Disease
Cleyson da Cruz Oliveira Barros, Alexandre Kanashiro, Gabriel Victor Lucena da Silva…·Fernando Q. Cunha
This study identifies PD-L1+ neutrophils as mediators of susceptibility to endotoxemia in MAFLD, showing that targeting IFN-γ or PD-L1 reduces inflammation and liver damage.
DOI 10.1101/2024.10.16.618651