Heikki Hyöty

This study shows that enterovirus infection induces TG2 via JAK-STAT signaling in intestinal epithelial cells, linking viral infection to celiac disease onset.

This study identifies Scinderin as a regulator of Golgi actin remodeling that coordinates GLP-1 and insulin secretion, linking intracellular trafficking defects to glucose homeostasis and diabetes.

This study standardizes the production of a soil and plant-based material, assesses its microbial content and safety, and demonstrates its potential to modulate the microbiome and immune system without adverse effects.

The paper identifies metabolic patterns in PBMCs associated with progression to islet autoimmunity and T1D using longitudinal metabolomics and metabolic modeling.

The paper identifies lipid profile changes in children before gluten introduction that associate with progression to celiac disease.