Keijo M. Viiri

This study shows that Coxsackievirus B3 evades CD8+ T-cell immunity by downregulating HLA Class I and viral peptide presentation, while inducing robust CD4+ T-cell responses and memory formation.

This study shows that enterovirus infection induces TG2 via JAK-STAT signaling in intestinal epithelial cells, linking viral infection to celiac disease onset.

This study identifies Scinderin as a regulator of Golgi actin remodeling that coordinates GLP-1 and insulin secretion, linking intracellular trafficking defects to glucose homeostasis and diabetes.

The paper identifies deep nuclear envelope invaginations (DINEs) in epithelial cells, showing they organize chromatin and gene activity in response to mechanical cues like crowding and tissue maturation.

This study shows that JAZF1-SUZ12 fusion protein disrupts PRC2 function, leading to altered histone modifications and gene expression during cell differentiation.

This study identifies Maf as a critical regulator of M cell differentiation and maturation, showing that its absence leads to impaired development and reduced Gp2 expression.

This study shows that Atoh8 regulates M cell differentiation, with its absence increasing M cell numbers and transcytosis capacity, affecting mucosal immunity.

The paper identifies Essrg as a necessary factor for Sox8-mediated M cell differentiation, regulated by PRC2 during intestinal M cell development.