C. elegans E3 ubiquitin ligase EBAX-1 promotes non-apoptotic linker cell-type death through target-directed miRNA degradation
Lauren Bayer Horowitz, Olya Yarychkivska, Yun Lü, Shai Shaham
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NYU Langone HealthORCID 0000-0003-0385-7555Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Lauren Bayer Horowitz, Olya Yarychkivska, Yun Lü, Shai Shaham
Olya Yarychkivska, Simin Liu, Lauren Bayer Horowitz…·Shai Shaham
The paper identifies MYRF-1 as a regulator of non-apoptotic linker cell death in C. elegans, showing its role in priming death through activation of pqn-41/polyQ.
Jung-Hwan Choi, Lauren Bayer Horowitz, Niels Ringstad
The paper shows that VST-1 antagonizes EAT-4/VGLUT to regulate glutamate release and chemotaxis in C. elegans.
Lauren Bayer Horowitz, Julia P. Brandt, Niels Ringstad
This study shows that autocrine insulin-like peptide signaling, regulated by neural activity and genetic programs, is essential for the development of chemosensory neurons in C. elegans.