Author

Emily R. Webb

Cancer Research UKORCID 0000-0001-9339-4544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Fraser Laing· 3 shared Morwenna MuiriD· 3 shared Valerie G. BruntoniD· 3 shared A. R. S. BlackiD· 1 shared Ajitha RajaniD· 1 shared Alan SerrelsiD· 1 shared Alex von KriegsheimiD· 1 shared Alexander E.P. LoftusiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Fraser Laing

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3 papers

Recent·Most cited

FAK Inhibition Remodels the Metastatic ECM and Restores CD8+ T Cell Trafficking and Immunosurveillance

Nicole D. Barth, Bo Peng, Michael Papanicolaou, Fatemeh Ahmadi Moughari, Camille L. Duran, Christopher S. McGinnis, John C. Dawson, Emily R. Webb, Morwenna Muir, Fraser Laing, Yookyung Jung, Xue‐Yan He, Ansuman T. Satpathy, Mikala Egeblad, Syed Aleem Haider, , Valerie G. Brunton

This paper shows that FAK inhibition remodels the metastatic ECM, enhancing CD8+ T cell infiltration and immunosurveillance in breast cancer.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology

FAK inhibitor treatment systemically regulates the glioblastoma immune environment via blocking monocyte trafficking

Emily R. Webb, A. R. S. Black, Giovana Carrasco, Muhammad Furqan, Robert L. Hollis, Alexander E.P. Loftus, Joel A Ochoa, Romain Enjalbert, Tara Best, Xiaozhong Peng, Morwenna Muir, Fraser Laing, Martin W. Lee, Sofian Al Shboul, Tongjie Wang, , Valerie G. Brunton

This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.

bioRxiv · Nov 26, 2025 · PreprintImmunology

USP18 Inhibition Enhances Type I Interferon Signalling and Immune Activation in the Tumour Microenvironment of Triple-Negative Breast Cancer

Chartinun Chutoe, Emily R. Webb, Morwenna Muir, Fraser Laing, Valerie G. Brunton, Alex von Kriegsheim

This study shows that inhibiting USP18 enhances type I interferon signaling and immune activation in TNBC, converting immunologically cold tumors into hot ones and improving immunotherapy efficacy.

bioRxiv · Sep 1, 2025 · PreprintCancer Biology