Author

Dongchang Sun

Zhejiang University of TechnologyORCID 0000-0003-0405-4623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Biao TangiD· 1 shared Chenyu Wang· 1 shared Hua YangiD· 1 shared Mengdie FangiD· 1 shared Mingyue FeiiD· 1 shared Ruiting Zhang· 1 shared Zhi-Zhi LiuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Biao TangORCID

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1 paper

Recent·Most cited

MicrobiologyApplied and Environmental MicrobiologyPeer-reviewedSep 10, 2024

Engineering probiotic Escherichia coli Nissle 1917 to block transfer of multiple antibiotic resistance genes by exploiting a type I CRISPR-Cas system

Mengdie Fang, Ruiting Zhang, Chenyu Wang…·Dongchang Sun

This paper engineers Escherichia coli Nissle 1917 to block antibiotic resistance gene transfer using a type I CRISPR-Cas system, showing efficacy in vitro and in zebrafish.

35 citationstop 4%

E. coligenetic perturbation / CRISPR

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