Cell BiologyNaturePeer-reviewed
The proteomic landscape of proteotoxic stress in a fibrogenic liver disease
Florian A. Rosenberger, Sophia Clara Mädler, Katrine Holtz Thorhauge…·Matthias Mann
This study uses spatial proteomics and machine learning to analyze AATD in human liver tissue, revealing peroxisomal upregulation and a terminal hepatocyte state with distinct proteomic signatures.
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