Caroline A M Weiss

The paper constructs a cell type-resolved proteomic atlas of the human body using Deep Visual Proteomics, revealing protein abundance patterns and uncovering cancer-testis antigens in oocytes.

This study uses single-cell spatial proteomics to map human liver zonation patterns and shows their disruption in fibrosis.

The paper shows that transcription arrest in mitochondria leads to the formation of RNA granules that protect mt-mRNAs and help restore OXPHOS balance.

This study uses spatial proteomics and machine learning to analyze AATD in human liver tissue, revealing peroxisomal upregulation and a terminal hepatocyte state with distinct proteomic signatures.

AlphaQuant improves proteoform regulation detection in bottom-up proteomics by using tree-based quantification and deep learning, revealing new patterns in mouse tissues.