Aleksander Ahm Krag

Sex-stratified adipose-liver circuits in human MASLD

This study identifies sex-specific transcriptional differences in liver and visceral adipose tissue in MASLD and shows coordinated cross-tissue states.

Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

This study examines transcriptional changes in human adipose tissue during weight loss from lifestyle and bariatric surgery, showing significant remodeling and reduced inflammation.

The proteomic landscape of proteotoxic stress in a fibrogenic liver disease

This study uses spatial proteomics and machine learning to analyze AATD in human liver tissue, revealing peroxisomal upregulation and a terminal hepatocyte state with distinct proteomic signatures.

Obesity- and age-dependent genetic regulation of the plasma proteome in children and adolescents

This study identifies genetic regulation of plasma proteins in children and adolescents, finding obesity- and age-dependent pQTLs and potential causal links to cardiometabolic traits.

Deep Proteome Profiling of Metabolic Dysfunction-Associated Steatotic Liver Disease

This study identifies protein biomarkers for MASLD using proteomics data from liver, blood, and adipose tissue, showing improved prediction models over existing methods.

Plasma Proteome Variation and its Genetic Determinants in Children and Adolescents

This study identifies genetic determinants of plasma protein levels in children and adolescents using MS-based proteomics, revealing extensive genetic impacts that persist into adulthood.

Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

This study shows that fecal microbial load, not disease, is the main driver of gut microbiome changes and identifies it as a major confounder in microbiome studies.

Describing the fecal metabolome in cryogenically collected samples from healthy participants.

The paper describes the fecal metabolome in cryogenically collected samples from healthy participants, identifying metabolites and their variation across different areas of the stool.