Author

Andrew M. Frank

Henry M. Jackson FoundationORCID 0000-0003-0411-7102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Clifton L. DalgardiD· 2 shared Matthew D. WilkersoniD· 2 shared Amanda J. LinkeiD· 1 shared Beth Flores· 1 shared Briana BentoniD· 1 shared Brianna R. DaleyiD· 1 shared Bridget A. FinniffiD· 1 shared Camille AlbaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Clifton L. DalgardORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of NeurotraumaPeer-reviewedNov 10, 2025

A spatial gene expression signature of the mouse brain post-injury at the focal point of contusion

Savannah Kounelis-Wuillaume, Andrew M. Frank, Emilie Goguet…·Martin L. Doughty

This study examines spatial gene expression changes in the mouse brain after focal TBI, identifying region-specific transcriptional responses and the role of immune cells in modulating post-injury gene activity.

1 citation

mousebulk RNA-seq

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Cancer BiologyCancer ResearchPeer-reviewedOct 22, 2024

SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma

Brianna R. Daley, Nancy E. Sealover, Bridget A. Finniff…·Robert L. Kortum

This study shows that SOS1 inhibition with BI-3406 enhances G12C inhibitor efficacy and delays resistance in lung adenocarcinoma by targeting resistance mechanisms and drug-tolerant persister cells.

20 citationstop 3%

humanexperimental assay

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GenomicsbioRxivPreprintJun 9, 2020

A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein

Marco A. Riojas, Andrew M. Frank, Nikhita P. Puthuveetil…·Sujatha Rashid

The paper reports a 27 nt deletion in SARS-CoV-2 ORF6 that alters the predicted 3D structure of p6, potentially affecting its function and localization.

20 citations

viruswhole-genome sequencing

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