Kyle M. Baumbauer

The paper identifies Avpr1a as a novel candidate gene for chronic visceral pain through genomic and functional analyses in mouse models and human patients.

This study shows that spinal cord injury rapidly alters nociceptor response properties, leading to increased sensitivity and spontaneous activity, contributing to chronic pain.

The paper uses optogenetics to assess how non-peptidergic C-fiber afferents contribute to aversive behaviors before and after nerve injury.

This study shows TIMP-1 reduces inflammatory pain through both MMP-dependent and receptor-mediated signaling mechanisms.

The paper uses single cell qPCR and functional assays to correlate gene expression with functional properties in identified sensory neurons, finding transcriptional heterogeneity within functional subgroups.