Cancer BiologyPLoS ONEPeer-reviewed
LAMP2A-dependent chaperone-mediated autophagy enhances oxidative stress resistance in gastric cancer cells through selective degradation of accumulated oxidized DJ-1
Shuangshuang Le, Tongtong Guo, Meng Yang…·Maogui Pang
This study shows that LAMP2A-dependent CMA enhances oxidative stress resistance in gastric cancer by degrading oxidized DJ-1, preventing apoptosis and promoting survival.
DOI 10.1371/journal.pone.0331823