Author

Shuangshuang Le

Chinese People's Liberation ArmyORCID 0000-0003-3431-8458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Maogui PangiD· 1 shared Meng Yang· 1 shared Tianjuan Tang· 1 shared Tongtong GuoiD· 1 shared Zheng YangiD· 1 shared Zhijie Liu· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Maogui PangORCID

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1 paper

Recent·Most cited

Cancer BiologyPLoS ONEPeer-reviewedMay 15, 2026

LAMP2A-dependent chaperone-mediated autophagy enhances oxidative stress resistance in gastric cancer cells through selective degradation of accumulated oxidized DJ-1

Shuangshuang Le, Tongtong Guo, Meng Yang…·Maogui Pang

This study shows that LAMP2A-dependent CMA enhances oxidative stress resistance in gastric cancer by degrading oxidized DJ-1, preventing apoptosis and promoting survival.

DOI 10.1371/journal.pone.0331823

humanproteomics

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