Liying Li

The paper uses yeast aging to map proteome changes across age, revealing structural determinants of age-sensitive remodeling and providing a resource for aging research.

The paper uses single-cell spatial proteomics in yeast to uncover molecular changes linked to aging hallmarks and their spatial organization.

This study shows that budding yeast adapts to long-term high temperature by reducing temperature-sensitive proteins, relocalizing the proteome, and altering protein conformations, which may confer new functions.