Author

Gavin Schlissel

Stanford MedicineORCID 0000-0003-0490-7438Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Anders S. HanseniD· 3 shared Pulin LiiD· 2 shared Christina J. Zhang· 1 shared Domenic N. NarducciiD· 1 shared J. Wade HarperiD· 1 shared Jingchuan LuoiD· 1 shared Jingjie HuiD· 1 shared Jonathan S. WeissmaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersDevelopmental Biology

Anders S. HansenORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 28, 2026

Failure to release from the ER translocon induces 60S ribosome degradation

Zebulon G. Levine, Stuti Khandwala, Christina J. Zhang…·Jonathan S. Weissman

The paper identifies a cell-state-dependent pathway for degrading ER-retained 60S ribosomal subunits through UFMylation loss and the action of TLSD1.

DOI 10.64898/2026.09.26.754687

humanproteomics

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Developmental BiologyScience AdvancesPeer-reviewedSep 9, 2026

Mechanistic tradeoffs between local and long-range signaling activity in natural and synthetic morphogens

Gavin Schlissel, Anders S. Hansen, Pulin Li

The paper investigates how lipid modifications affect Hedgehog morphogen signaling and gradient formation, revealing a tradeoff between local enrichment and long-range diffusion.

DOI 10.1126/sciadv.aef4578

experimental assay

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Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 27, 2024

Diffusion barriers imposed by tissue topology shape morphogen gradients

Gavin Schlissel, Miram Meziane, Domenic N. Narducci…·Pulin Li

The paper shows SCUBE1 expands Hedgehog gradients by enabling transient diffusion through cell gaps, revealing a topology-limited diffusion mechanism for morphogen signaling.

23 citations

statistical model

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