Author

Jingchuan Luo

Johns Hopkins UniversityORCID 0000-0002-6450-7172Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jef D. BoekeiD· 2 shared Weimin ZhangiD· 2 shared Adhithi R. Raghavan· 1 shared Agnès ThierryiD· 1 shared Allison F. MoyeriD· 1 shared Anders S. HanseniD· 1 shared Andreas HochwageniD· 1 shared Andrew D’Avino· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersSynthetic Biology

Jef D. BoekeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Failure to release from the ER translocon induces 60S ribosome degradation

Zebulon G. Levine, Stuti Khandwala, Christina J. Zhang, Kelsey L. Hickey, Julia Joung, Jingjie Hu, Yi Hua Chen, Jingchuan Luo, Anders S. Hansen, J. Wade Harper, Gavin Schlissel, Jonathan S. Weissman

The paper identifies a cell-state-dependent pathway for degrading ER-retained 60S ribosomal subunits through UFMylation loss and the action of TLSD1.

bioRxiv · Sep 28, 2026 · PreprintCell Biology

Synthetic chromosome fusion: effects on genome structure and function

Jingchuan Luo, Luís A. Vale-Silva, Adhithi R. Raghavan, Guillaume Mercy, Jonna Heldrich, Xiaoji Sun, Mingyu Kenneth Li, Weimin Zhang, Neta Agmon, Kun Yang, Jitong Cai, Giovanni Stracquadanio, Agnès Thierry, Yu Zhao, Camila Coelho, , Jef D. Boeke

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

bioRxiv · Aug 10, 2023 · PreprintSynthetic Biology

Stable twin rDNA loci form a single nucleolus in brewer's yeast

Luciana Lazar‐Stefanita, Jingchuan Luo, Max A. B. Haase, Weimin Zhang, Jef D. Boeke

This study shows that twin rDNA loci in brewer's yeast form a single nucleolus and reveals position-dependent size changes in rDNA loci.

bioRxiv · Jun 14, 2022 · PreprintGenomics