GenomicsNature CommunicationsPeer-reviewed
Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells
Patricia Gerdes, Sue Mei Lim, Adam D. Ewing…·Geoffrey J. Faulkner
The paper identifies retrotransposon insertions as the main source of mutations in mouse induced pluripotent stem cells, showing hypomethylation of LINE-1 elements and their impact on gene regulation.
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