Author

Olga Dethlefsen

Stockholm UniversityORCID 0000-0003-0502-1401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Anastasia EmmanouilidouiD· 2 shared Benedikt von der HeydeiD· 2 shared Erik IngelssoniD· 2 shared Eugenia Mazzaferro· 2 shared Giulia GaudenziiD· 2 shared Hannah L. BrookeiD· 2 shared Marcel den HoediD· 2 shared Ola HermansoniD· 2 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Anastasia EmmanouilidouORCID

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4 papers

Recent·Most cited

GenomicsScientific ReportsPeer-reviewedJul 16, 2020

Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9/based approach

Benedikt von der Heyde, Anastasia Emmanouilidou, Eugenia Mazzaferro…·Marcel den Hoed

The paper uses a CRISPR/Cas9-based approach in zebrafish to identify genes affecting heart rate variability and confirms the role of known genes while highlighting a novel gene.

91 citationstop 1%

zebrafishimaging

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NeuroscienceMolecular PsychiatryPeer-reviewedNov 13, 2019

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors

Giulia Zanni, Shinobu Goto, Adamantia F. Fragopoulou…·Klas Blomgren

This study shows lithium treatment can reverse irradiation-induced impairments in hippocampal neurogenesis in mice even when started weeks after irradiation.

45 citations

mousestatistical model

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GenomicsbioRxivPreprintJun 11, 2019

Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis

Manoj K Bandaru, Anastasia Emmanouilidou, Petter Ranefall…·Marcel den Hoed

The paper develops a zebrafish pipeline to study dyslipidemia and atherosclerosis, identifying potential causal genes and showing drug effects.

10 citations

zebrafishexperimental assay

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Molecular BiologybioRxivPreprintMar 16, 2019

Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitors

Giulia Gaudenzi, Olga Dethlefsen, Julian Walfridsson, Ola Hermanson

The paper identifies genes co-regulated by Pax6 and KDM5C in neural progenitors, including Notch signaling regulators, through chromatin analysis and functional validation.

1 citation

humanChIP-seq

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