Author

Daniel E. Huddleston

Emory UniversityORCID 0000-0003-0503-3736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexa F. Iannitelli· 1 shared Amanda Lea SharpeiD· 1 shared Anu KorukondaiD· 1 shared Arielle Segal· 1 shared Bernard MulveyiD· 1 shared David WeinshenkeriD· 1 shared Dean P. JonesiD· 1 shared Douglas Ian WalkeriD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alexa F. Iannitelli

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 7, 2023

Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus

Leslie Hassanein, Bernard Mulvey, Harris E. Blankenship…·Alexa F. Iannitelli

This study shows that tyrosinase-induced neuromelanin accumulation in mouse locus coeruleus neurons causes hyperactivity, transcriptional changes, and degeneration, mimicking early stages of Alzheimer's and Parkinson's disease.

19 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintMay 22, 2018

Levodopa and dopamine dynamics in Parkinson’s disease metabolomics

Rachel C. Branco, William Ellsworth, Megan M. Niedzwiecki…·Gary Wright Miller

This study uses metabolomics to identify metabolic differences between Parkinson’s disease and control patients, highlighting the impact of levodopa on observed variations.

2 citations

humanmetabolomics

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