Author

Vivek B. Raina

Columbia University Irving Medical CenterORCID 0000-0003-0507-9208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aidan M. Jessop· 2 shared Eric C. GreeneiD· 2 shared Katherine Morse· 2 shared Michael T. PetassiiD· 2 shared Razvan Matei· 2 shared Stefan Y. KimiD· 2 shared Yeonoh ShiniD· 2 shared Gerben VaderiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Aidan M. Jessop

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3 papers

Recent·Most cited

GeneticsJournal of Biological ChemistryPeer-reviewedDec 8, 2025

Lineage-specific amino acids define functional attributes of the protomer-protomer interfaces for the Rad51 and Dmc1 recombinases

Michael T. Petassi, Yeonoh Shin, Aidan M. Jessop…·Eric C. Greene

The paper compares Rad51 and Dmc1 recombinases using structural and functional analyses to show differences in their interfacial amino acids and evolutionary trajectories.

2 citations

yeastprotein structure

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedSep 11, 2025

Structural basis for Rad54- and Hed1-mediated regulation of Rad51 during the transition from mitotic to meiotic recombination

Yeonoh Shin, Michael T. Petassi, Aidan M. Jessop…·Eric C. Greene

The paper identifies Rad51 interaction motifs in Rad54 and Hed1, and solves their CryoEM structures to explain their roles in regulating Rad51 activity during mitosis and meiosis.

5 citations

cryo-EMexperimental assay

𝕏 PostBluesky

GeneticsCurrent BiologyPeer-reviewedSep 10, 2020

Homeostatic control of meiotic G2/prophase checkpoint function by Pch2 and Hop1

Vivek B. Raina, Gerben Vader

The paper reveals that the Pch2-Hop1 module regulates meiotic checkpoint function by both promoting and silencing checkpoint responses depending on cellular context.

41 citations

yeastexperimental assay

𝕏 PostBluesky