H. Westley Phillips

The paper combines electrophysiology and single-cell sequencing to study postnatal development of human neocortical neurons, identifying BK channels as key drivers of physiological changes.

The paper isolates and characterizes two postnatal human neural stem cell subsets, showing their fate biases and decline in frequency over time.

The paper identifies de novo mutations contributing to meningomyelocele risk by analyzing trios and finding damaging mutations in 22.3% of cases.

This study identifies 69 mutated genes in malformations of cortical development using multiomic profiling of 317 brain resections and single-cell sequencing.