Mitochondrial COX4I2 drives pericyte-dependent inflammation and emphysema
Claudia F. Garcia Castro, Vidya Srokshna Balasubramanian Lakshmi, Stefan Hadžić…·Natascha Sommer
This study shows that COX4I2 in pericytes drives inflammation and emphysema in COPD by increasing mtROS, and its deletion protects against these effects.