Cell BiologyNature CommunicationsPeer-reviewed
mTOR dysregulation induces IL6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis
Roya Babaei‐Jadidi, Debbie Clements, Yixin Wu…·Simon R. Johnson
This study shows mTOR dysregulation in LAM causes IL6 production and senescence in AT2 cells, impairing lung repair, and suggests targeting IL6 may help.
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