Robert Lea

The paper shows that oscillatory co-expression of HES1 and HES5 allows hybrid states in a bistable transcription factor motif by enabling phase-locking and entrainment.

The paper investigates YAP1 variants' role in ocular coloboma using in vitro and organoid studies, showing how missense variants affect YAP1-TEAD binding and transcriptional activity.

The paper investigates how cellular protrusions in mouse spinal cord neural progenitors enable long-distance Notch signaling, affecting HES5 expression patterns.

The paper shows that cell coupling compensates for altered Her6 dynamics in zebrafish neural progenitors, maintaining phenotypic robustness despite single-cell expression changes.

The paper shows that miR-9 optimizes noise in the Her6 oscillator, enabling cell state progression in zebrafish hindbrain neurogenesis.