Molecular BiologybioRxivPreprint
Direct monitoring of unfolded nascent polypeptides by the CCR4-NOT complex contributes to protein quality control through selective mRNA deadenylation and decay
Guillaume Caulier, Fabienne Mauxion, Bertrand Séraphin
The paper identifies the role of the CCR4-NOT complex in recognizing unfolded nascent polypeptides and triggering mRNA deadenylation and decay to maintain protein quality control in yeast.
DOI 10.64898/2026.10.08.757698