Bertrand Séraphin

This study shows Pho92 interacts with Not1 to recruit the CCR4-NOT complex to m6A-containing mRNAs, modulating meiosis in S. cerevisiae.

The paper identifies the role of the CCR4-NOT complex in recognizing unfolded nascent polypeptides and triggering mRNA deadenylation and decay to maintain protein quality control in yeast.

This study shows that TBPL2-dependent transcription is essential for maintaining cellular organization in growing oocytes by regulating RNA stability and decay machinery.

The paper identifies HELZ2, a new human RNB family protein expressed from a non-canonical initiation codon, which functions as an interferon-regulated 3'-5' exoribonuclease with RNA degradation activity.

This study shows DIS3 mutations in multiple myeloma increase AID-dependent IgH translocations by altering chromatin interactions and RNA processing.

This study shows that the m6A-reader Pho92 in S. cerevisiae promotes meiotic progression by accelerating the down-regulation of specific mRNAs during meiotic recombination.