Functional brain age prediction suggests accelerated aging in preclinical familial Alzheimer's disease, irrespective of fibrillar amyloid-beta pathology
Julie Gonneaud, Alex T. Baria, Alexa Pichet Binette…·The Dominantly Inherited Alzheimer Network (DIAN)
The paper develops a model to predict brain aging from resting state fMRI and finds accelerated brain aging in preclinical Alzheimer's disease, independent of amyloid-beta pathology.