Author

Christoph Grundner

University of WashingtonORCID 0000-0003-0596-6798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Vishant Mahendra BoradiaiD· 2 shared A Saleh· 1 shared Amy Wu· 1 shared Andrew FrandoiD· 1 shared Ashutosh TripathiiD· 1 shared Junxi CheniD· 1 shared Kyu Young RheeiD· 1 shared Lindsay V. ClarkiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

Vishant Mahendra BoradiaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 5, 2026

Inorganic sulfate transport by the Mycobacterium tuberculosis PE22/PPE36 complex

Ashutosh Tripathi, Vishant Mahendra Boradia, Amy Wu…·Christoph Grundner

This study identifies the PE22/PPE36 complex in Mycobacterium tuberculosis as a sulfate uptake system, showing its role in sulfur acquisition and metabolic homeostasis.

DOI 10.64898/2026.06.04.730267

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologyNature CommunicationsPeer-reviewedApr 24, 2026

PE/PPE proteins contribute to Mycobacterium tuberculosis drug resistance

Vishant Mahendra Boradia, Junxi Chen, Andrew Frando…·Christoph Grundner

This study identifies PE/PPE proteins in Mycobacterium tuberculosis as contributors to drug resistance through genetic association and in vitro experiments.

3 citationstop 2%

experimental assaydrug response / drug discovery

𝕏 PostBluesky

GeneticsJournal of Biological ChemistryPeer-reviewedJul 21, 2021

An Alternative, Cas12a-based CRISPR Interference System for Mycobacteria

Neil D. Fleck, Christoph Grundner

This paper introduces a Cas12a-based CRISPRi system for mycobacteria that enables efficient multigene regulation and studies genetic interactions in Mtb.

21 citations

experimental assayperturbation response prediction

𝕏 PostBluesky