Author

Yeonji Chang

Whitehead Institute for Biomedical ResearchORCID 0000-0003-0602-863XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Ankur JainiD· 2 shared Michael R. Das· 2 shared Cameron O. SchmitziD· 1 shared Colson TomberliniD· 1 shared Kelsey L. FarenhemiD· 1 shared Nan ZhangiD· 1 shared Rachel AndersoniD· 1 shared Reuben A. SaundersiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Ankur JainORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedJan 30, 2024

CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs

Rachel Anderson, Michael R. Das, Yeonji Chang…·Ankur Jain

This study identifies that CAG repeat expansions create new splice acceptor sites, leading to aberrant repeat-containing RNAs that are translated via canonical AUG-initiated mechanisms.

8 citations

humanmultiome

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Molecular BiologybioRxivPreprintAug 30, 2021

Flanking sequences regulate the toxicity, non-ATG translation, and aggregation of RNA with tandem CAG Repeats

Michael R. Das, Yeonji Chang, Reuben A. Saunders…·Ankur Jain

The paper shows that flanking sequences of CAG repeat-containing RNA affect its toxicity, non-ATG translation, and cytoplasmic aggregation, linking these to neurodegenerative disease mechanisms.

DOI 10.1101/2021.08.30.458106

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