Tracy R. Melzer

The paper evaluates if individualized head models improve source-space EEG functional connectivity predictions of cognition in Parkinson's disease, finding standard templates are sufficient.

The paper identifies thalamic volume reductions in Alzheimer's disease and shows their utility in classifying cognitive status and reclassifying patients.

The paper introduces DunedinPACNI, a brain MRI-based aging measure that predicts dementia conversion, morbidity, and mortality.

This paper introduces a stacking machine learning approach to improve predictability, test-retest reliability, and generalisability of brain-wide associations for cognitive abilities using multimodal MRI data.

The paper examines how functional topography of neocortical networks in midlife relates to covariation in motor and cognitive abilities, finding that motor ability reflects functional topography differences while hearing does not.

The paper examines the association between retinal neuronal layer thickness and brain structural integrity in midlife, finding thinner retinal layers correlate with reduced brain structural measures.

The paper demonstrates a data harmonization process for memory testing across 53 studies, reducing inter-site variance while preserving covariate effects.

The paper identifies a common pattern of reduced neocortical thickness across multiple psychiatric disorder categories and the general psychopathology factor.

The paper identifies key neuropsychological tests that predict dementia conversion in Parkinson's disease patients using logistic regression and elastic net methods.

The paper examines microstructural changes in thalamic nuclei across cognitive stages of Parkinson's disease and finds increased mean diffusivity correlates with cognitive decline, particularly in the lateral dorsal nucleus.

The paper identifies genetic loci associated with human cortical structure and finds genetic correlations with neuropsychiatric disorders.

This study shows that older brain-age in midlife is linked to accelerated biological aging and cognitive decline, supporting brain-age as a biomarker while highlighting its potential to reflect lifelong CNS variation.

The paper replicates structural brain alterations linked to the p factor in a longitudinal cohort, finding support for cerebello-thalamo-cortical circuit and visual association cortex associations but not cerebellar morphology.

This paper introduces General Functional Connectivity (GFC) to improve reliability and heritability of intrinsic connectivity estimates by combining resting-state and task fMRI data.

This study finds that white matter hyperintensities (WMHs) are common in midlife and are associated with lower IQ and greater cognitive decline from childhood to midlife.