Author

Brad L. Lackford

National Institutes of HealthORCID 0000-0003-0637-4428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Brian D. BennettiD· 3 shared Guang HuiD· 3 shared Christopher B. GeyeriD· 1 shared Debra L. SilveriD· 1 shared Hongyao YuiD· 1 shared Jacob R. EgoliD· 1 shared Jiajia WangiD· 1 shared Jiajia WangiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersDevelopmental Biology

Brian D. BennettORCID

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedAug 1, 2025

Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance

Qing Chen, Safia Malki, Xiaojiang Xu…·Guang Hu

This study shows that CNOT3 is essential for maintaining spermatogonial stem cells in mice by repressing differentiation factors and regulating the redox pathway.

5 citations

mousestatistical model

𝕏 PostBluesky

NeurosciencePLoS BiologyPeer-reviewedFeb 6, 2025

mRNA stability fine tunes gene expression in the developing cortex to control neurogenesis

Lucas D. Serdar, Jacob R. Egol, Brad L. Lackford…·Debra L. Silver

The paper shows that RNA stability controls neurogenesis in the developing cortex by regulating gene expression through the CCR4-NOT complex.

14 citationstop 5%

mousebulk RNA-seq

𝕏 PostBluesky

Developmental BiologyNucleic Acids ResearchPeer-reviewedJun 9, 2021

INO80 promotes H2A.Z occupancy to regulate 1 cell fate transition in pluripotent stem cells

Hongyao Yu, Jiajia Wang, Brad L. Lackford…·Guang Hu

34 citations

mouseChIP-seq

𝕏 PostBluesky