Author

Lucas D. Serdar

Duke Medical CenterORCID 0000-0002-4574-1668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Debra L. SilveriD· 2 shared Brad L. LackfordiD· 1 shared Brian D. BennettiD· 1 shared Brooke R. D’ArcyiD· 1 shared Camila Manso MussoiD· 1 shared Chia-Fang LeeiD· 1 shared Guang HuiD· 1 shared Jacob R. EgoliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Debra L. SilverORCID

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2 papers

Recent·Most cited

Subcellular transcriptome of radial glia reveals compartmentalized control of cortical development

Brooke R. D’Arcy, Camila Manso Musso, Chia-Fang Lee, Lucas D. Serdar, Stephany Perez-Sanchez, Virginia Fernández, Vı́ctor Borrell, Debra L. Silver

The paper identifies a subcellular transcriptome in radial glia, revealing localized gene regulation and its role in cortical development.

bioRxiv · Oct 10, 2025 · PreprintNeuroscience

mRNA stability fine tunes gene expression in the developing cortex to control neurogenesis

Lucas D. Serdar, Jacob R. Egol, Brad L. Lackford, Brian D. Bennett, Guang Hu, Debra L. Silver

The paper shows that RNA stability controls neurogenesis in the developing cortex by regulating gene expression through the CCR4-NOT complex.

PLoS Biology · Feb 6, 2025Peer-reviewedNeuroscience