BiophysicsbioRxivPreprint
Serial femtosecond crystallography reveals the pH-driven allosteric mechanism of hexamer glargine
Esra Beyarslan Ayan, Madan Kumar Shankar, Elek Telek…·Takehiko Tosha
This study reveals the pH-driven allosteric mechanism of hexamer glargine using serial femtosecond crystallography and multiscale analyses, showing a structural transition linked to delayed release.
DOI 10.64898/2026.04.07.716775