Aleksey Lazarenkov

The paper identifies a TET2-AGO2 regulatory axis that links epigenetic remodeling to myeloid commitment and leukemia progression.

The paper establishes a cause-and-effect relationship between DNA methylation at the IL1RN promoter and gene expression, showing its impact on myeloid cell fate and inflammatory response.

This study identifies the IFNγ pathway's role in accelerating iPSC reprogramming and X-chromosome reactivation through STAT3 signaling and TET-mediated demethylation.

This study shows p53 rapidly changes 3D chromatin structure to regulate gene transcription, identifying 340 new direct target genes.