Author

Lucía Fanlo

Josep Carreras Leukaemia Research InstituteORCID 0000-0002-8364-9520Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Neuroscience· 1

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:Hi-C· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alfonso ValenciaiD· 2 shared Biola M. JavierreiD· 2 shared Blanca UrmenetaiD· 2 shared Llorenç RovirosaiD· 2 shared Ahlam AlqahtaniiD· 1 shared Ainoa Planas‐RiverolaiD· 1 shared Aleksey LazarenkoviD· 1 shared Alvaro Alcalde-MerinoiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenomics

Alfonso ValenciaORCID

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3 papers

Recent·Most cited

Three-Dimensional Epigenome Roadmap of Human B-cell Differentiation Uncovers Mechanisms of Humoral Immunity and Oncogenesis

Raul de Haro-Blazquez, Laureano Tomás-Daza, Lucía Fanlo, Paula López-Martí, Nicolas Byrne-Alvarez, Llorenç Rovirosa, Blanca Valero, Juan Ochoteco Asensio, Maria Rigau, Galina Medvedeva, Lucía Álvarez-González, Blanca Urmeneta, Ainoa Planas‐Riverola, J. Carbonell, Teresa Robert-Finestra, , Biola M. Javierre

This paper creates a 3D epigenomic roadmap of human B-cell differentiation, revealing regulatory mechanisms in immunity and cancer.

bioRxiv · Dec 24, 2025 · PreprintGenomics

p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response

François Serra, Andrea Nieto-Aliseda, Lucía Fanlo, Llorenç Rovirosa, Mónica Cabrera-Pasadas, Aleksey Lazarenkov, Blanca Urmeneta, Alvaro Alcalde-Merino, E. Nola, Andrei L. Okorokov, Peter Fraser, Mariona Graupera, Sandra D. Castillo, José Luis Sardina, Alfonso Valencia, Biola M. Javierre

This study shows p53 rapidly changes 3D chromatin structure to regulate gene transcription, identifying 340 new direct target genes.

Nature Communications · Apr 1, 2024Peer-reviewedGenomics

Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting metastasis

Lucía Fanlo, Soledad Gómez‐González, Irene Sangrador, Emmanuel L. Gautier, Susana Usieto, Elena Rebollo, Mònica Vilà-Ubach, Angel Montero Carcaboso, Toni Celià-Terrassa, Cinzia Emilia Lavarino, Elisa Martı́, Gwenvaël Le Dréau

The paper identifies a transcriptional signature distinguishing low- and high-risk neuroblastomas and shows that NXPH1/-NRXN signaling inhibits metastasis while promoting tumor growth.

bioRxiv · Nov 26, 2021 · PreprintNeuroscience