Lydia E. Kavraki

This study compares spatial immune architectures in tumor and tumor-adjacent tissues of early-stage NSCLC, finding distinct immune cell densities, spatial patterns, and associations with genomic features and patient outcomes.

The paper identifies TCRs targeting HER2 mutations in NSCLC, showing they recognize mutant epitopes and maintain cytotoxic activity, offering a potential immunotherapy strategy.

EnGens provides a unified framework for generating and analyzing protein conformational ensembles using existing methods and tools.

DINC-COVID provides a webserver for ensemble docking of SARS-CoV-2 proteins with flexible receptors and ligands, generating and scoring plausible binding modes.