Author

Huan Du

Cornell UniversityORCID 0000-0003-0728-7844Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Huan Du1 paper · University of Electronic Science and Technology of China

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Fenghua HuiD· 3 shared Mariela Nunez Santos· 2 shared Cha Yang· 1 shared Charlene Hsu· 1 shared Haiyuan YuiD· 1 shared Junke ZhangiD· 1 shared Lianne Jillian TrigianiiD· 1 shared Man Ying WongiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Fenghua HuORCID

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3 papers

Recent·Most cited

NeuroscienceActa NeuropathologicaPeer-reviewedMar 25, 2024

Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice

Tuancheng Feng, Huan Du, Cha Yang…·Fenghua Hu

This study shows that loss of TMEM106B worsens Tau pathology and neurodegeneration in PS19 mice.

21 citationstop 3%

mouseexperimental assay

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NeuroscienceMolecular NeurodegenerationPeer-reviewedFeb 4, 2022

Differential regulation of progranulin derived granulin peptides

Tingting Zhang, Huan Du, Mariela Nunez Santos…·Fenghua Hu

The paper identifies differential regulation of specific granulin peptides and their glycosylation patterns in relation to lysosomal protease activity and physiological/pathological conditions.

33 citations

humanproteomics

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NeuroscienceLife Science AlliancePeer-reviewedJun 8, 2021

A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses

Huan Du, Man Ying Wong, Tingting Zhang…·Fenghua Hu

This study shows that PGRN deficiency affects amyloid-beta levels and microglial activation in a sex- and age-dependent manner, influencing lysosomal activity and inflammation in Alzheimer's disease.

19 citations

mouseexperimental assay

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