Lianne Jillian Trigiani

This study uses THG microscopy to track subcortical myelin degradation in a mouse MS model, finding increased intranodal distances and a new quantitative metric for early detection.

The paper identifies differential regulation of specific granulin peptides and their glycosylation patterns in relation to lysosomal protease activity and physiological/pathological conditions.

This study shows that netrin-1 expressed by neurons in the adult brain is critical for spatial memory formation, as its deletion impairs memory without affecting anxiety or grooming behavior.