Author

Patrick W.B. Derksen

University Medical Center UtrechtORCID 0000-0003-0732-7762Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert J. R. HeckiD· 1 shared Ana Marques· 1 shared Ana Rita Araujo· 1 shared Andreia G. Silva· 1 shared Angelo D. Meringa· 1 shared Anne-Marie FortieriD· 1 shared Annick Nouwens· 1 shared Antoine A KhaliliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Albert J. R. HeckORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 21, 2025

Multi-omics analysis of TNBC organoids identifies phosphorylation of the membrane trafficking machinery as a key event associated with FER-mediated invasion

Carolien Elshout, Goncalo Mota, Joana Cunha…·Sandra Tavares

The paper identifies phosphorylation of membrane trafficking regulators, particularly SEC16A, as key to FER-mediated invasion in TNBC organoids.

DOI 10.64898/2025.12.18.695070

humanproteomics

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Cancer BiologybioRxivPreprintNov 19, 2024

Sensitivity to Vγ9Vδ2TCR T cells is imprinted after single mutations during early oncogenesis

Astrid Cleven, Angelo D. Meringa, Péter Brázda…·Zsolt Sebestyén

This study shows that single mutations during early oncogenesis can upregulate BTN2A1, enabling Vγ9Vδ2 TCR binding, but full activation requires subsequent phosphorylation of BTN3A1.

4 citations

humanexperimental assay

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